There were no accidental fire deaths in Rutland, Leicester and Leicestershire in 2014/15.
Leicestershire Fire and Rescue Service said this was a first since it started recording the figures.
Chief fire and rescue officer Dave Webb said: “Our firefighting crews remain a vital part of the effort to save lives, and they are ready to respond every time they are needed.
“However, the best way to save lives is to stop fires from starting the first place, and if they do start, to make sure people get early warning from a smoke alarm and that they know their escape plan.”
The service has a team of community safety educators to spread the message to homes and schools.
Mr Webb said: “They are an essential part of reducing fire risk and without them we would not be able to make our zero deaths announcement today.”